Name: Tagraxofusp-erzs Injection
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Why is this medication prescribed?
Tagraxofusp-erzs injection is used to treat blastic plasmacytoid dendritic cell neoplasm (BPDCN; a blood cancer that causes skin lesions, and may spread to the bone marrow and lymphatic system) in adults and children 2 years of age and older. Tagraxofusp-erzs is in a class of medications called CD123 cytotoxin. It works by killing cancer cells.
Other uses for this medicine
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before receiving tagraxofusp-erzs,
- tell your doctor and pharmacist if you are allergic to tagraxofusp-erzs, any other medications, or any of the ingredients in tagraxofusp-erzs injection. Ask your pharmacist for a list of the ingredients.
- tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements and herbal products you are taking or plan to take. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- tell your doctor if you are pregnant, or plan to become pregnant. You must take a pregnancy test within 7 days before starting treatment. You should not become pregnant during your treatment with tagraxofusp-erzs. Use effective birth control during treatment and for 7 days after your final dose. If you become pregnant while receiving tagraxofusp-erzs, call your doctor.
- tell your doctor if you are breastfeeding. You should not breastfeed during your treatment with tagraxofusp-erzs and for 7 days after your final dose.
What side effects can this medication cause?
Tagraxofusp-erzs may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- extreme tiredness
- decreased appetite
- sore throat
- pain in back, arms, or legs
- difficulty falling asleep or staying asleep
- feeling nervous or confused
- nose bleed
- small red, brown, or purple spots on the skin
Some side effects can be serious. If you experience any of these symptoms or those listed in the IMPORTANT WARNING section call your doctor immediately or get emergency medical treatment:
- rash, itching, difficulty breathing, mouth sores or swelling
- extreme tiredness, yellowing of skin or eyes, loss of appetite, pain in the upper right part of the stomach
- fever, chills
- fast heartbeat
- blood in urine
Tagraxofusp-erzs may cause other side effects. Call your doctor if you have any unusual problems while receiving this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).