Romosozumab-aqqg Injection

Name: Romosozumab-aqqg Injection

How should this medicine be used?

Romosozumab-aqqg injection comes as a solution to be injected subcutaneously (under the skin) into in your stomach area, upper arm, or thigh. It is usually injected once a month by a healthcare provider for 12 doses.

Other uses for this medicine

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Before receiving romosozumab-aqqg injection,

  • tell your doctor and pharmacist if you are allergic to romosozumab-aqqg, any other medications, or any of the ingredients in romosozumab-aqqg injection. Ask your pharmacist or check the Medication Guide for a list of the ingredients.
  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: angiogenesis inhibitors such as axitinib (Inlyta), bevacizumab (Avastin), everolimus (Afinitor, Zortress), pazopanib (Votrient), sorafenib (Nexavar), or sunitinib (Sutent); bisphosphonates such as alendronate (Binosto, Fosamax), etidronate, or ibandronate (Boniva); cancer chemotherapy medications; denosumab (Prolia); or a steroid medication such as dexamethasone, methylprednisolone (Medrol), and prednisone (Rayos). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • tell your doctor if you have low levels of calcium. Your doctor will probably tell you not to receive romosozumab-aqqg injection.
  • tell your doctor if you have or have ever had kidney disease or are being treated with hemodialysis (treatment to remove waste from the blood when the kidneys are not working).
  • tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. Romosozumab-aqqg injection is only approved for treatment of postmenopausal women. If you become pregnant while receiving romosozumab-aqqg injection, call your doctor immediately.
  • you should know that romosozumab-aqqg injection may cause osteonecrosis of the jaw (ONJ, a serious condition of the jaw bone), especially if you need to have dental surgery or treatment while you are using the medication. A dentist should examine your teeth and perform any needed treatments, including cleaning, before you start to use romosozumab-aqqg injection. Be sure to brush your teeth and clean your mouth properly while you are using romosozumab-aqqg injection. Talk to your doctor before having any dental treatments while you are using this medication.

What special dietary instructions should I follow?

While you are receiving romosozumab-aqqg injection, it is important that you get enough calcium and vitamin D. Your doctor may prescribe supplements if your dietary intake is not enough.

In case of emergency/overdose

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.