Name: Omidria

Uses of Omidria

Omidria is a combination of prescription medications that is added to irrigation solution during eye surgery. It is available as a single product containing 2 medications: phenylephrine and ketorolac.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.


  • Omeros Corporation

Omidria Drug Class

Omidria is part of the drug class:

  • Sympathomimetics used as decongestants

Side Effects of Omidria

Serious side effects have been reported with Omidria. See the “Omidria Precautions” section.

Common side effects of Omidria include the following:

  • eye inflammation
  • increased intraocular pressure
  • eye irritation
  • foreign body sensation in the eye

This is not a complete list of Omidria side effects. Ask your doctor or pharmacist for more information.

Tell your doctor if you have any side effect that bothers you or that does not go away.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Omidria Interactions

No drug interactions have been determined by the manufacturer. However, you should tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Not all drug interactions are known or reported and new drug interactions are continually being reported.

Inform MD

Before taking Omidria, tell your doctor about all of your medical conditions. Especially tell your doctor if you:

  • are allergic to Omidria or to any of the ingredients in the combination product
  • have or had had sensitivities or allergies to acetylsalicylic acid (Aspirin) or other non-steroidal anti-inflammatory drugs such as ibuprofen (Advil), naproxen (Aleve), indomethacin (Indocin), meloxicam (Mobic), or celecoxib (Celebrex)
  • are pregnant or breastfeeding

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.

Omidria and Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant.

The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X - are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.

Omidria falls into category C. No studies have been done in animals with this combination product and no well-controlled studies have been done in pregnant women. Omidria should be given to a pregnant woman only if clearly needed.

Omidria Usage

Use Omidria exactly as prescribed.

This medication is available in an injectable form to be diluted in ophthalmic irrigation solution.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Very bad eye irritation.
  • Very bad headache.
  • Very bad dizziness.

How Supplied/Storage and Handling

Omidria is supplied as a sterile solution concentrate in a clear, 5-mL glass, single-patient-use vial containing 4 mL of sterile solution.

Omidria is supplied in a multi-pack containing:

4 single-patient-use vials: NDC 62225-600-04 or

10 single-patient-use vials: NDC 62225-600-10

Storage: Store at 20˚ to 25˚C (68˚ to 77˚F). Protect from light.