Omacetaxine (Subcutaneous Route)

Name: Omacetaxine (Subcutaneous Route)

US Brand Name

  1. Synribo

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of omacetaxine injection in the pediatric population. Safety and efficacy have not been established.

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For injection dosage form:
    • For chronic myeloid leukemia:
      • Adults—Dose is based on body surface area and must be determined by your doctor. At first, 1.25 milligrams (mg) per square meter (m(2)) of body surface area injected under the skin every 12 hours for 14 days. The dose is repeated every 28 days. Your doctor may adjust the schedule to one shot every 12 hours for 7 days during the 28-day cycle.
      • Children—Use and dose must be determined by your doctor.

Missed Dose

This medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

To store syringes at home:

  • Use an ice pack or cooler to carry the syringes from your doctor's office.
  • If placed in a refrigerator, use the syringes within 6 days after you receive them. Do not allow food or drinks to touch the syringes.
  • If placed at room temperature, use the syringes within 12 hours after you receive them.

Do not throw the used syringes, needles, or other supplies in a household trash or recycle container. Put all of the used supplies in the biohazard container and return it to your doctor for disposal.

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