Nix

Name: Nix

Why is this medication prescribed?

Permethrin is used to treat scabies ('mites that attach themselves to the skin) in adults and children 2 months of age and older. Over-the-counter permethrin is used to treat lice (small insects that attach themselves to the skin on the head) in adults and children 2 months of age and older. Permethrin is in a class of medications called scabicides and pediculicides. It works by killing lice and mites.

How should this medicine be used?

Permethrin comes as a cream to apply to the skin. Over-the-counter permethrin comes as a lotion to apply to the scalp and hair. Permethrin cream is usually applied to the skin in one treatment, but occasionally a second treatment is necessary. Permethrin lotion is usually applied to the skin in one or two treatments, but occasionally three treatments are necessary. If live mites are seen two weeks (14 days) after the first treatment with permethrin cream, then a second treatment should be applied. If live lice are seen one week after the first treatment with over-the-counter permethrin lotion, then a second treatment should be applied. Follow the directions on your prescription label or the package label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use permethrin exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.

Permethrin should only be used on the skin or hair and scalp. Avoid getting permethrin in your eyes, nose, ears, mouth, or vagina. Do not use permethrin on your eyebrows or eyelashes.

If permethrin gets in your eyes, flush them with water right away. If your eyes are still irritated after flushing with water, call your doctor or get medical help right away.

To use permethrin cream, follow these steps:

  1. Apply a thin layer of cream all over your skin from your neck down to your toes (including the soles of your feet). Be careful to apply cream in all skins folds, such as between your toes and fingers or around your waist or buttocks.
  2. For treatment of babies or adults over 65 years of age, the cream should also be applied to the scalp or hairline, temples, and forehead.
  3. You may need to use all of the cream in the tube to cover your body.
  4. Leave the cream on your skin for 8-14 hours.
  5. After 8-14 hours have passed, wash off the cream by bathing or showering.
  6. Your skin may be itchy after treatment with permethrin cream. This does not mean your treatment did not work. If you see live mites 14 days or more after treatment, then you will need to repeat the treatment process.

To use the lotion, follow these steps:

  1. Wash your hair with shampoo and rinse with water. Do not use a conditioner or a shampoo that contains a conditioner because your treatment will not work as well.
  2. Dry your hair with a towel until just damp.
  3. Shake permethrin lotion well right before use to mix the medication evenly.
  4. Use a towel to cover your face and eyes. Be sure to keep your eyes closed during this treatment. You may need to have an adult help you apply the lotion.
  5. Apply permethrin lotion to your hair and scalp area. Begin to apply the lotion behind your ears and at the back of your neck and then cover all of the hair on your head and scalp.
  6. Keep the lotion on your hair and scalp for 10 minutes after you finish applying permethrin lotion. You should use a timer or clock to track the time.
  7. Rinse your hair and scalp with warm water in a sink. You should not use a shower or bathtub to rinse the lotion away because you do not want to get the lotion over the rest of your body.
  8. Dry your hair with a towel and comb out tangles.
  9. You and anyone who helped you apply the lotion should wash your hands carefully after the application and rinsing steps.
  10. A lice comb may also be used to remove the dead lice and nits (empty egg shells) after this treatment. You may also need to have an adult help you to do this.
  11. If you see live lice on your head 7 days or more after treatment, repeat this entire process.

After using permethrin, sanitize all the clothing, underwear, pajamas, hats, sheets, pillowcases, and towels you have used recently. These items should be washed in very hot water or dry-cleaned. You should also wash combs, brushes, hairs clips and other personal care items in hot water.

Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

Dosing & Uses

Dosage Forms & Strengths

cream

  • 5%

liquid

  • 1%

lotion

  • 1%

Scabies

Cream: Apply from head to toe, leave on for 8-14 hr, rinse; may reapply in 7 days if live mites reappear

Single application usually curative

Head Lice & Nits (Eggs)

Lotion/cream rinse/liquid: apply to washed hair, leave on 10 min, rinse and comb out nits and eggs; may repeat in 7 days if lice or nits still present

Single application usually curative.

Dosage Forms & Strengths

cream

  • 5%

liquid

  • 1%

lotion

  • 1%

Scabies & Head Lice

<2 months

  • Safety & efficacy not established

>2 months

  • Scabies: Apply cream from head to toe; leave on for 8-14 hr, rinse; may reapply in 7 days if live mites reappear; single application usually curative
  • Head Lice & Nits (Eggs): Apply lotion/cream/liquid to washed hair, leave on 10 min, rinse and comb out nits and eggs; may repeat in 7 days if lice or nits still present; single application usually curative

Drug interactions

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use.Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

Missed dose

Not applicable.

Storage

Store at room temperature between 59-77 degrees F (15-25 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

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Reviewed on 4/16/2014 References

What do I need to tell my doctor BEFORE I take Nix?

  • If you have an allergy to permethrin, chrysanthemums, or any other part of Nix (permethrin cream rinse and lotion).
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.

This medicine may interact with other drugs or health problems.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

How is this medicine (Nix) best taken?

Use Nix as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • Follow how to use as you have been told by the doctor or read the package insert.
  • Do not take this medicine by mouth. Use on your skin only. Keep out of your mouth, nose, and eyes (may burn).
  • Wash your hands before and after use.
  • Clean affected part before use. Make sure to dry well.
  • Wash all bedding, towels, and recently worn clothes in hot water or have them dry cleaned.
  • Shampoo hair, rinse, and towel dry before use. Use a shampoo without a conditioner.
  • Shake well before use.
  • Cover eyes and face with a towel.
  • Lightly coat hair and scalp.
  • Work into hair and scalp gently.
  • Leave on for 10 minutes.
  • Do not cover head while cream rinse or lotion is on hair.
  • After 10 minutes, put a little bit of warm water on hair and lather.
  • Rinse fully.
  • Wash your hands after use.
  • Dry with a towel.
  • Use special nit comb or tweezers to get rid of dead nits (lice eggs) from hair.

What do I do if I miss a dose?

  • Put on a missed dose as soon as you think about it.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Trouble breathing.
  • A burning or tingling feeling that is not normal.
  • Eye irritation.
  • Very bad irritation where Nix is used.

What are some other side effects of Nix?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Itching. Talk to the doctor about what to do.
  • Irritation where this medicine is used.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

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