Name: Nitrek

Nitrek Overview

Nitroglycerin is a prescription medication used to treat or prevent episodes of angina (sudden chest pain). Nitroglycerin belongs to a group of drugs called nitrates which work by relaxing (widening) blood vessels making it easier for the heart to pump blood.

This medication comes in tablet form to be dissolved under the tongue or between the cheek and gum at the first sign of chest pain. The dose may be repeated every 5 minutes until chest pain is relieved. Seek emergency medical attention if the pain persists after 3 doses.

Common side effects of nitroglycerin include headache, dizziness, and weakness.

Nitrek and Pregnancy

Tell your doctor if you are pregnant. It is not known if nitroglycerin will harm your unborn baby.

For Healthcare Professionals

Applies to nitroglycerin: buccal tablet extended release, intravenous solution, oral capsule extended release, rectal ointment, sublingual powder, sublingual spray, sublingual tablet, transdermal film extended release, transdermal ointment


The most common side effect is headache.[Ref]

Nervous system

Very common (10% or more): Headache (up to 64%)
Common (1% to 10%): Dizziness, lightheadedness, syncope, vertigo, drowsiness
Rare (0.1% to 0.01%): Severe and prolonged headache
Very rare (less than 0.01%): Cerebral ischemia
Frequency not reported: Faintness, somnolence[Ref]


Common (1% to 10%): Hypotension, angina increased, paradoxical bradycardia, tachycardia, orthostatic hypotension, blood pressure decreased, facial flushing
Uncommon (0.1 to 1%): Circulatory collapse
Rare (less than 0.1%): Bradycardia, cyanosis, flushing, heart rate increase
Frequency not reported: Crescendo angina, rebound hypertension, palpitations, hypertension, decreased arterial oxygen tension, severe arterial hypotension with bradycardia, transient flushing[Ref]


Common (1% to 10%): Nausea, vomiting
Rare (0.01% to 0.1%): Dry mouth
Very rare (less than 0.01%): Heartburn, halitosis
Frequency not reported: Abdominal pain, retching, lip and tongue swelling[Ref]


Uncommon (0.1% to 1%): Dermatitis contact, erythema, pruritus, burning, irritation, eczema, urticaria
Rare (0.01 to 0.1%): Allergic skin reactions, rash
Very rare (less than 0.01%): Exfoliative dermatitis, drug rash
Frequency not reported: Cutaneous flushing, diaphoresis, angioedema
Postmarketing reports: Rash generalized[Ref]


Common (1% to 10%): Asthenia, weakness
Frequency not reported: Retrosternal discomfort[Ref]


Rare (less than 0.1%): Hypersensitivity reactions, anaphylaxis
Frequency not reported: Allergic reaction, anaphylactoid reaction[Ref]


Common (1% to 10%): Restlessness
Frequency not reported: Apprehension[Ref]


Very rare (less than 0.01%): Impairment of respiration
Frequency not reported: Hypoxemia, dyspnea[Ref]


Very rare (less than 0.01%): Methemoglobinemia[Ref]


Rare (less than 0.1%): Blurred vision
Frequency not reported: Increased ocular pressure[Ref]


Frequency not reported: Muscle twitching[Ref]

Some side effects of Nitrek may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.