Nicotine (Nasal Route)

Name: Nicotine (Nasal Route)

US Brand Name

  1. Nicotrol NS


Nicotine nasal spray is used to help you stop smoking. Nicotine is absorbed in the nose and enters the blood stream. This replaces the nicotine you would get from smoking and makes the withdrawal effects from not smoking less severe. The amount of nicotine is decreased over time until use is stopped.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Spray


Appropriate studies have not been performed on the relationship of age to the effects of nicotine nasal spray in the pediatric population. Safety and efficacy have not been established. Small amounts of nicotine can cause serious unwanted effects in children, and the nasal spray contains enough nicotine to cause problems, including used bottles.


Although appropriate studies on the relationship of age to the effects of nicotine nasal spray have not been performed in the geriatric population, no geriatric-specific problems have been documented to date. However, elderly patients are more likely to have age-related kidney, liver, or heart problems, which may require caution and an adjustment in the dose for patients receiving nicotine nasal spray.

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For the nasal dosage form (spray):
    • To help you stop smoking:
      • Adults—At first, 1 spray in each nostril (1 milligram (mg)). The dose may be repeated 1 to 4 times during the same hour if needed. Your doctor may adjust the dose based on the number of cigarettes you smoke per day or based on how well you tolerate the medicine. However, the total dose is usually not more than 40 mg per day (40 sprays in each nostril). Your dose will be gradually reduced before stopping treatment completely.
      • Children—Use is not recommended.