Minims Pilocarpine 2%

Name: Minims Pilocarpine 2%

Proper Use of pilocarpine

This section provides information on the proper use of a number of products that contain pilocarpine. It may not be specific to Minims Pilocarpine 2%. Please read with care.

To use the eye drop form of pilocarpine:

  • First, wash your hands. Tilt the head back and, pressing your finger gently on the skin just beneath the lower eyelid, pull the lower eyelid away from the eye to make a space. Drop the medicine into this space. Let go of the eyelid and gently close the eyes. Do not blink. Keep the eyes closed and apply pressure to the inner corner of the eye with your finger for 1 or 2 minutes to allow the medicine to be absorbed by the eye.
  • Immediately after using the eye drops, wash your hands to remove any medicine that may be on them.
  • To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface (including the eye). Also, keep the container tightly closed.

To use the eye gel form of pilocarpine:

  • First, wash your hands. Tilt the head back and, pressing your finger gently on the skin just beneath the lower eyelid, pull the lower eyelid away from the eye to make a space. Squeeze a thin strip of gel into this space. A 1½-cm (approximately ½-inch) strip of gel is usually enough, unless you have been told by your doctor to use a different amount. Let go of the eyelid and gently close the eyes. Keep the eyes closed for 1 or 2 minutes to allow the medicine to be absorbed by the eye.
  • Immediately after using the eye gel, wash your hands to remove any medicine that may be on them.
  • To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface (including the eye). After using the eye gel, wipe the tip of the gel tube with a clean tissue and keep the tube tightly closed.

To use the eye insert form of pilocarpine:

  • This medicine usually comes with patient directions. Read them carefully before using this medicine.
  • If you think this medicine unit may be damaged, do not use it. If you have any questions about this, check with your health care professional.
  • If the unit seems to be releasing too much medicine into your eye, remove it and replace with a new unit. If you have any questions about this, check with your doctor.

Use this medicine only as directed. Do not use more of it and do not use it more often than your doctor ordered. To do so may increase the chance of too much medicine being absorbed into the body and the chance of side effects.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For eye drop dosage form:
    • For chronic glaucoma:
      • Adults and children—One drop one to four times a day.
    • For acute angle-closure glaucoma:
      • Adults and children—One drop every five to ten minutes for three to six doses. Then one drop every one to three hours until eye pressure is reduced.
  • For eye gel dosage form:
    • For glaucoma:
      • Adults and teenagers—Use once a day at bedtime.
      • Children—Use and dose must be determined by your doctor.
  • For eye insert dosage form:
    • For glaucoma:
      • Adults and children—Insert one ocular system every seven days.
      • Infants—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Store the eye system form of this medicine in the refrigerator. Keep from freezing. Store the 3.5-gram size (of the gel form) at room temperature.

For the Consumer

Applies to pilocarpine ophthalmic: ophthalmic device, ophthalmic gel/jelly, ophthalmic solution, ophthalmic suspension

Along with its needed effects, pilocarpine ophthalmic may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur while taking pilocarpine ophthalmic:

Symptoms of too much medicine being absorbed into the body
  • Increased sweating
  • muscle tremors
  • nausea, vomiting, or diarrhea
  • troubled breathing or wheezing
  • watering of mouth
Less common or rare
  • Eye pain

Some side effects of pilocarpine ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Blurred vision or change in near or far vision
  • decrease in night vision
Less common
  • Eye irritation
  • headache or browache

Usual Adult Dose for Glaucoma (Open Angle)

Reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension: One drop of 1%, 2%, or 4% solution applied in the eye(s) up to four times a day

Comments:
-Patients who are naive to this drug should be started on the 1% concentration.
-The frequency of instillation and concentration of this drug is determined by the severity of the elevated intraocular pressure and miotic response of the patient.
-Patients may be instructed to perform punctal occlusion for 2 minutes after instillation to limit systemic exposure to this drug.
-This drug may be used in combination with beta-blockers, carbonic anhydrase inhibitors, sympathomimetics, or hyperosmotic agents.
-If more than one topical ophthalmic drug is being used, the drugs should be administered at least 5 minutes apart.

Prevention of Postoperative Elevated IOP Associated with Laser Surgery: One drop of the 1%, 2%, or 4% solution (or two drops administered five minutes apart) should be applied in the eye(s) 15 to 60 minutes prior to surgery

Comments:
-This drug may be used in combination with beta-blockers, carbonic anhydrase inhibitors, sympathomimetics or hyperosmotic agents.
-If more than one topical ophthalmic drug is being used, the drugs should be administered at least 5 minutes apart.

Usual Pediatric Dose for Production of Miosis

Under 2 years:
One drop of 1% solution should be applied in the eye(s) three times a day

2 years or older:
Reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension: One drop of 1%, 2% or 4% solution applied in the eye(s) up to four times a day
Management of Acute Angle-Closure Glaucoma: One drop of the 1% or 2% solution applied in the eye(s) up to three times over a 30-minute period
Prevention of Postoperative Elevated IOP Associated with Laser Surgery: One drop of the 1%, 2% or 4% solution (or two drops administered five minutes apart) should be applied in the eye(s) 15 to 60 minutes prior to surgery

Comments:
-Patients who are naive to this drug should be started on the 1% concentration.
-The frequency of instillation and concentration of this drug is determined by the severity of the elevated intraocular pressure and miotic response of the patient.
-This drug may be used in combination with beta-blockers, carbonic anhydrase inhibitors, sympathomimetics or hyperosmotic agents.
-If more than one topical ophthalmic drug is being used, the drugs should be administered at least 5 minutes apart.
-Prior to use, treatment with secretory suppressants and hyperosmotic agents may be needed to lower IOP below 50 mmHg and relieve iris ischemia.
-If laser iridoplasty or iridomy is used to break the attack, one drop of the 4% solution should be administered prior to the procedure.
-Following laser iridoplasty, one drop of the 1% solution should be administered four times daily until an iridotomy can be performed.

Uses:
-Reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension
-Management of acute angle-closure glaucoma
-Prevention of postoperative elevated IOP associated with laser surgery
-Induction of miosis

Dialysis

Data not available

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