Micrainin

Name: Micrainin

Micrainin Drug Class

Micrainin is part of the drug classes:

  • Other agents for local oral treatment

  • Platelet aggregation inhibitors excl. heparin

  • Salicylic acid and derivatives

  • Carbamates

Commonly used brand name(s)

In the U.S.

  • Equagesic
  • Micrainin

Available Dosage Forms:

  • Tablet

Therapeutic Class: Salicylate, Aspirin Combination

Pharmacologic Class: NSAID

Chemical Class: Carbamate

Uses For Micrainin

Meprobamate and aspirin combination is used to relieve pain, anxiety, and tension in certain disorders or diseases.

This medicine is available only with your doctor's prescription.

Before Using Micrainin

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Do not give a medicine containing aspirin to a child or teenager with a fever or other symptoms of a virus infection, especially flu or chickenpox, without first discussing this with your child's doctor. This is very important because aspirin may cause a serious illness called Reye's syndrome in children or teenagers with fever caused by a virus infection, especially flu or chickenpox. Children who do not have a virus infection may also be more sensitive to the effects of aspirin (contained in this combination medicine), especially if they have a fever or have lost large amounts of body fluid because of vomiting, diarrhea, or sweating. This may increase the chance of side effects during treatment.

Geriatric

Elderly people may be especially sensitive to the effects of meprobamate and aspirin. This may increase the chance of side effects during treatment.

Pregnancy

Pregnancy Category Explanation
All Trimesters D Studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy in a life threatening situation or a serious disease, may outweigh the potential risk.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

  • Defibrotide
  • Dichlorphenamide
  • Influenza Virus Vaccine, Live
  • Ketorolac

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Acarbose
  • Aceclofenac
  • Acemetacin
  • Alfentanil
  • Alipogene Tiparvovec
  • Alprazolam
  • Alteplase, Recombinant
  • Amiloride
  • Amineptine
  • Amitriptyline
  • Amitriptylinoxide
  • Amobarbital
  • Amoxapine
  • Amtolmetin Guacil
  • Anagrelide
  • Anisindione
  • Apixaban
  • Aprobarbital
  • Argatroban
  • Bendroflumethiazide
  • Benzthiazide
  • Betrixaban
  • Bivalirudin
  • Bromazepam
  • Bromfenac
  • Bromopride
  • Bufexamac
  • Bumetanide
  • Buprenorphine
  • Butabarbital
  • Butalbital
  • Butorphanol
  • Carbinoxamine
  • Carisoprodol
  • Celecoxib
  • Chloral Hydrate
  • Chlordiazepoxide
  • Chlorothiazide
  • Chlorpropamide
  • Chlorthalidone
  • Chlorzoxazone
  • Choline Salicylate
  • Cilostazol
  • Citalopram
  • Clobazam
  • Clomipramine
  • Clonazepam
  • Clonixin
  • Clopamide
  • Clopidogrel
  • Clorazepate
  • Codeine
  • Cyclopenthiazide
  • Cyclosporine
  • Dabigatran Etexilate
  • Danaparoid
  • Dantrolene
  • Desipramine
  • Desirudin
  • Desmopressin
  • Desvenlafaxine
  • Dexibuprofen
  • Dexketoprofen
  • Diazepam
  • Diazoxide
  • Dibenzepin
  • Diclofenac
  • Dicumarol
  • Diflunisal
  • Digoxin
  • Dihydrocodeine
  • Dipyrone
  • Dothiepin
  • Doxepin
  • Doxylamine
  • Droxicam
  • Duloxetine
  • Edoxaban
  • Eplerenone
  • Eptifibatide
  • Escitalopram
  • Eslicarbazepine Acetate
  • Estazolam
  • Ethacrynic Acid
  • Ethchlorvynol
  • Etodolac
  • Etofenamate
  • Etoricoxib
  • Felbinac
  • Fenoprofen
  • Fentanyl
  • Fepradinol
  • Feprazone
  • Feverfew
  • Flibanserin
  • Floctafenine
  • Fluconazole
  • Flufenamic Acid
  • Flunitrazepam
  • Fluoxetine
  • Flurazepam
  • Flurbiprofen
  • Fluvoxamine
  • Fondaparinux
  • Fospropofol
  • Furosemide
  • Ginkgo
  • Glimepiride
  • Glipizide
  • Glyburide
  • Gossypol
  • Halazepam
  • Heparin
  • Hydrochlorothiazide
  • Hydrocodone
  • Hydroflumethiazide
  • Hydromorphone
  • Ibuprofen
  • Imipramine
  • Indapamide
  • Indomethacin
  • Ketazolam
  • Ketoprofen
  • Lepirudin
  • Levomilnacipran
  • Levorphanol
  • Lithium
  • Lofepramine
  • Lorazepam
  • Lormetazepam
  • Lornoxicam
  • Loxoprofen
  • Lumiracoxib
  • Meclizine
  • Meclofenamate
  • Medazepam
  • Mefenamic Acid
  • Melitracen
  • Meloxicam
  • Meperidine
  • Mephenesin
  • Mephobarbital
  • Meprobamate
  • Metaxalone
  • Metformin
  • Methadone
  • Methocarbamol
  • Methohexital
  • Methotrexate
  • Methyclothiazide
  • Metolazone
  • Midazolam
  • Milnacipran
  • Morniflumate
  • Morphine
  • Morphine Sulfate Liposome
  • Nabumetone
  • Nalbuphine
  • Naproxen
  • Nateglinide
  • Nefazodone
  • Nepafenac
  • Nicorandil
  • Niflumic Acid
  • Nimesulide
  • Nimesulide Beta Cyclodextrin
  • Nitrazepam
  • Nortriptyline
  • Opipramol
  • Oxaprozin
  • Oxazepam
  • Oxycodone
  • Oxymorphone
  • Oxyphenbutazone
  • Parecoxib
  • Paroxetine
  • Pemetrexed
  • Pentazocine
  • Pentobarbital
  • Pentosan Polysulfate Sodium
  • Pentoxifylline
  • Periciazine
  • Phenindione
  • Phenobarbital
  • Phenprocoumon
  • Phenylbutazone
  • Piketoprofen
  • Piracetam
  • Piroxicam
  • Polythiazide
  • Pralatrexate
  • Pranoprofen
  • Prasugrel
  • Prazepam
  • Primidone
  • Proglumetacin
  • Propofol
  • Propyphenazone
  • Proquazone
  • Protein C
  • Protriptyline
  • Quazepam
  • Remifentanil
  • Repaglinide
  • Reteplase, Recombinant
  • Rivaroxaban
  • Rofecoxib
  • Salicylic Acid
  • Salsalate
  • Secobarbital
  • Sertraline
  • Sodium Oxybate
  • Sodium Salicylate
  • Spironolactone
  • Sufentanil
  • Sulindac
  • Tacrolimus
  • Tapentadol
  • Temazepam
  • Tenoxicam
  • Thiopental
  • Tianeptine
  • Tiaprofenic Acid
  • Ticagrelor
  • Ticlopidine
  • Tirofiban
  • Tolazamide
  • Tolbutamide
  • Tolfenamic Acid
  • Tolmetin
  • Torsemide
  • Tramadol
  • Treprostinil
  • Triamterene
  • Triazolam
  • Trichlormethiazide
  • Trimipramine
  • Valdecoxib
  • Varicella Virus Vaccine
  • Venlafaxine
  • Vilazodone
  • Vortioxetine
  • Warfarin
  • Xipamide
  • Zolpidem

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Acebutolol
  • Atenolol
  • Betamethasone
  • Betaxolol
  • Bisoprolol
  • Captopril
  • Carteolol
  • Carvedilol
  • Celiprolol
  • Cortisone
  • Delapril
  • Dexamethasone
  • Enalaprilat
  • Enalapril Maleate
  • Esmolol
  • Imidapril
  • Labetalol
  • Levobunolol
  • Lisinopril
  • Methylprednisolone
  • Metipranolol
  • Metoprolol
  • Nadolol
  • Nebivolol
  • Nitroglycerin
  • Oxprenolol
  • Paramethasone
  • Penbutolol
  • Pindolol
  • Practolol
  • Prednisolone
  • Prednisone
  • Probenecid
  • Propranolol
  • Sotalol
  • Streptokinase
  • Tamarind
  • Temocapril
  • Tenecteplase
  • Timolol
  • Triamcinolone
  • Valproic Acid

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

  • Ethanol

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Alcohol abuse (or history of) or
  • Drug abuse or dependence (or history of)—Dependence on meprobamate may develop
  • Anemia or
  • Stomach ulcer or other stomach problems—Aspirin may make your condition worse
  • Asthma, allergies, and nasal polyps (history of) or
  • Kidney disease or
  • Liver disease—The chance of side effects may be increased.
  • Epilepsy—The risk of seizures may be increased
  • Gout—Aspirin may make this condition worse and may also lessen the effects of some medicines used to treat gout
  • Hemophilia or other bleeding problems—The chance of bleeding may be increased by aspirin
  • Porphyria—Meprobamate may make the condition worse

Proper Use of meprobamate and aspirin

This section provides information on the proper use of a number of products that contain meprobamate and aspirin. It may not be specific to Micrainin. Please read with care.

Take this medicine with food or a full glass (8 ounces) of water to lessen stomach irritation.

Do not take this medicine if it has a strong vinegar-like odor. This odor means the aspirin in it is breaking down. If you have any questions about this, check with your health care professional.

Take this medicine only as directed by your doctor . Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much meprobamate is taken, it may become habit-forming. Also, taking too much aspirin may cause stomach problems or lead to medical problems because of an overdose.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • Adults—Oral, 1 or 2 tablets three or four times a day, as needed.
  • Children up to 12 years of age: Use is not recommended.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Micrainin Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Rare
  • Wheezing, shortness of breath, troubled breathing, or tightness in chest
Symptoms of overdose
  • Any loss of hearing
  • bloody urine
  • confusion (severe)
  • convulsions (seizures)
  • diarrhea (severe or continuing)
  • dizziness or lightheadedness (continuing)
  • drowsiness (severe)
  • fast or deep breathing
  • hallucinations (seeing, hearing, or feeling things that are not there)
  • headache (severe or continuing)
  • increased sweating
  • nausea or vomiting (continuing)
  • nervousness or excitement (severe)
  • ringing or buzzing in ears (continuing)
  • slow heartbeat
  • slurred speech
  • staggering
  • stomach pain (severe or continuing)
  • unexplained fever
  • unusual or uncontrolled flapping movements of the hands, especially in elderly patients
  • unusual thirst
  • vision problems
  • weakness (severe)
Symptoms of overdose in children
  • Changes in behavior
  • drowsiness or tiredness (severe)
  • fast or deep breathing

Check with your doctor as soon as possible if any of the following side effects occur:

Rare
  • Bloody or black, tarry stools
  • confusion
  • skin rash, hives, or itching
  • sore throat and fever
  • unusual bleeding or bruising
  • unusual excitement
  • unusual tiredness or weakness
  • vomiting of blood or material that looks like coffee grounds

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Drowsiness
  • heartburn or indigestion
  • nausea with or without vomiting
  • stomach pain (mild)
Less common
  • Blurred vision or change in near or distant vision
  • dizziness or lightheadedness
  • headache

After you stop using this medicine, it may still produce some side effects that need attention. During this period of time, check with your doctor immediately if you notice the following side effects:

  • Clumsiness or unsteadiness
  • confusion
  • convulsions (seizures)
  • hallucinations (seeing, hearing, or feeling things that are not there)
  • increased dreaming
  • muscle twitching
  • nausea or vomiting
  • nervousness or restlessness
  • nightmares
  • trembling
  • trouble in sleeping

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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