- Butabarbital action
- Butabarbital missed dose
- Butabarbital dosage
- Butabarbital pediatric dose
- Butabarbital 6 mg
- Butabarbital drug
Mechanism of Action
Interferes with transmission of impulses from the thalamus to the cortex; depresses sensory cortex & decreases motor activity
Half-Life: ~100 hr
Duration: 6-8 hr
Onset: 45-60 min
Enzymes induced: CYP1A2, CYP2C9/10, CYP3A4
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
When treating insomnia, take butabarbital only when you are getting ready to sleep at least during 7 or 8 hours.
Use Labeled Indications
Sedative/Hypnotic: Use as a sedative or hypnotic.
Hypersensitivity to barbiturates or any component of the formulation; ; history of manifest or latent porphyria
Documentation of allergenic cross-reactivity for barbiturates is limited. However, because of similarities in chemical structure and/or pharmacologic actions, the possibility of cross-sensitivity can not be ruled out with certainty.
Dosing Renal Impairment
There are no dosage adjustments provided in the manufacturer’s labeling; reduced doses are recommended.
Usual Pediatric Dose for Sedation
Preoperative sedation: 2 to 6 mg/kg orally, up to a maximum of 100 mg.
Liver Dose Adjustments
No specific dose adjustment guidelines have been suggested; however, caution and a dose reduction are recommended in patients with liver dysfunction.
Data not available
CAS Registry Number
Hypnotics and Sedatives