What is B-Tuss (chlorpheniramine, hydrocodone, and phenylephrine)?
Chlorpheniramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.
Hydrocodone is a narcotic cough medicine.
Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).
Chlorpheniramine, hydrocodone, and phenylephrine is a combination medicine used to treat runny or stuffy nose, sinus congestion, and cough caused by the common cold or flu.
Chlorpheniramine, hydrocodone, and phenylephrine may also be used for purposes not listed in this medication guide.
What should I discuss with my healthcare provider before taking this medicine?
Do not use this medicine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, and tranylcypromine.
You should not use chlorpheniramine, hydrocodone, and phenylephrine if you are allergic to it, or if you have recently used alcohol, sedatives, tranquilizers, or other narcotic medications.
To make sure this medicine is safe for you, tell your doctor if you have:
blockage in your digestive tract (stomach or intestines);
diarrhea, inflammatory bowel disease;
a colostomy or ileostomy;
liver or kidney disease;
bladder obstruction or other urination problems;
a head injury or brain tumor;
asthma, COPD, sleep apnea, or other breathing disorder;
a thyroid disorder;
pheochromocytoma (tumor of the adrenal gland);
low blood pressure; or
if you are dehydrated.
It is not known whether this medicine will harm an unborn baby. If you use hydrocodone while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks. Tell your doctor if you are pregnant or plan to become pregnant.
Chlorpheniramine, hydrocodone, and phenylephrine can pass into breast milk and may harm a nursing baby. You should not breast-feed while using this medicine.
How should I take this medicine?
Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Hydrocodone may be habit-forming. Never share this medicine with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it. Selling or giving away this medicine is against the law.
Misuse of habit-forming medicine can cause addiction, overdose, or death. Selling or giving away this medicine is against the law.
You may take this medication with or without food.
Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.
Store at room temperature away from moisture and heat.
Keep track of the amount of medicine used from each new bottle. Hydrocodone is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.
Usual Pediatric Dose for Cough and Nasal Congestion
Chlorpheniramine/hydrocodone/phenylephrine 2 mg-6 mg-12 mg/5 mL oral liquid:
6 to 11 yrs: 5 mL orally every 4 to 6 hours not to exceed 25 mL daily
12 yrs or older: 5 to 10 mL orally every 4 to 6 hours not to exceed 50 mL daily.
Chlorpheniramine/hydrocodone/phenylephrine 2.5 mg-3.5 mg-8 mg/5 mL oral liquid:
Chlorpheniramine/hydrocodone/phenylephrine 2.5 mg-3.25 mg-8 mg/5 mL oral liquid:
Chlorpheniramine/hydrocodone/phenylephrine 2 mg-2.5 mg-10 mg/5 mL oral liquid:
6 to 11 yrs: 5 mL orally every 4 to 6 hours not to exceed 20 mL daily
12 yrs or older: 10 mL orally every 4 to 6 hours not to exceed 40 mL daily.
Chlorpheniramine/hydrocodone/phenylephrine 3 mg-5 mg-7.5 mg/5 mL oral liquid:
6 to 11 yrs: 2.5 to 5 mL orally every 4 to 6 hours not to exceed 20 mL daily
12 yrs or older: 5 to 10 mL orally every 4 to 6 hours not to exceed 40 mL daily.
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available