Adipex

Name: Adipex

Commonly used brand name(s)

In the U.S.

  • Adipex
  • Adipex-P
  • Atti-Plex P
  • Fastin
  • Ionamin
  • Lomaira
  • Phentercot
  • Phentride
  • Pro-Fast

Available Dosage Forms:

  • Capsule, Extended Release
  • Capsule
  • Tablet, Disintegrating
  • Tablet

Therapeutic Class: Appetite Suppressant, Centrally Acting

Chemical Class: Amphetamine Related

Before Using Adipex

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Use of phentermine is not recommended in children 16 years of age and younger. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of phentermine in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving phentermine.

Pregnancy

Pregnancy Category Explanation
All Trimesters X Studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities. This drug should not be used in women who are or may become pregnant because the risk clearly outweighs any possible benefit.

Breast Feeding

Studies in women breastfeeding have demonstrated harmful infant effects. An alternative to this medication should be prescribed or you should stop breastfeeding while using this medicine.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

  • Furazolidone
  • Iproniazid
  • Isocarboxazid
  • Linezolid
  • Methylene Blue
  • Moclobemide
  • Nialamide
  • Phenelzine
  • Procarbazine
  • Rasagiline
  • Safinamide
  • Selegiline
  • Sibutramine
  • Tranylcypromine

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Fenfluramine

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Agitated state (very nervous or anxious) or
  • Arrhythmias (abnormal heart rhythms), history of or
  • Arteriosclerosis (hardening of the arteries), serious or
  • Congestive heart failure, history of or
  • Drug abuse or dependence, history of or
  • Glaucoma or
  • Heart or blood vessel disease (eg, coronary artery disease), history of or
  • Hypertension (high blood pressure) that is not controlled, history of or
  • Hyperthyroidism (overactive thyroid) or
  • Stroke, history of—Should not be used in patients with these conditions.
  • Allergy to tartrazine—Suprenza™ contains tartrazine. Patients with this condition may have an allergic reaction.
  • Heart valve disease or
  • Hypertension (high blood pressure) or
  • Pulmonary hypertension (elevated pressure in the lungs)—Use with caution. May make these conditions worse.
  • Kidney disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

Important information

Do not use Adipex-P if you are pregnant or breast-feeding a baby.

You should not take Adipex-P if you have a history of heart disease (coronary artery disease, heart rhythm problems, congestive heart failure, stroke), severe or uncontrolled high blood pressure, overactive thyroid, glaucoma, a history of pulmonary hypertension, if you are in an agitated state, or if you have a history of drug or alcohol abuse.

Do not use Adipex-P if you have taken a MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

Before taking this medicine

Do not use Adipex-P if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

You should not take Adipex-P if you are allergic to phentermine, or if you have:

  • a history of heart disease (coronary artery disease, heart rhythm problems, congestive heart failure, stroke);

  • a history of pulmonary hypertension;

  • severe or uncontrolled high blood pressure;

  • overactive thyroid;

  • glaucoma;

  • if you are pregnant or breast-feeding;

  • if you are in an agitated state;

  • if you have a history of drug or alcohol abuse; or

  • if you are allergic to other diet pills, amphetamines, stimulants, or cold medications.

Taking Adipex-P together with other diet medications such as fenfluramine (Phen-Fen) or dexfenfluramine (Redux) can cause a rare fatal lung disorder called pulmonary hypertension. Do not take phentermine with any other diet medications without your doctor's advice.

To make sure you Adipex-P is safe for you, tell your doctor if you have:

  • high blood pressure;

  • diabetes;

  • kidney disease;

  • a thyroid disorder; or

  • if you are allergic to aspirin or to yellow food dye (FD & C Yellow No. 5, or tartrazine).

Phentermine may be habit forming. Never share Adipex-P with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.

FDA pregnancy category X. Weight loss during pregnancy can harm an unborn baby, even if you are overweight. Do not use Adipex-P if you are pregnant.

Phentermine can pass into breast milk and may harm a nursing baby. You should not breast-feed while taking Adipex-P.

Do not give this medication to a child younger than 16 years old.

How should I take Adipex-P?

Take Adipex-P exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Adipex-P can be taken with or without food.

To prevent sleep problems, take this medication early in the day, no later than 6:00pm.

Talk with your doctor if you have increased hunger or if you otherwise think the medication is not working properly. Taking more of this medication will not make it more effective and can cause serious, life-threatening side effects.

Adipex-P should be taken only for a short time, such as a few weeks.

Do not stop using Adipex-P suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using Adipex-P.

Store at room temperature away from moisture and heat.

Keep track of the amount of medicine used from each new bottle. Phentermine is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of phentermine can be fatal.

What other drugs will affect Adipex-P?

Taking this medicine with other stimulant drugs that make you restless or hyperactive can worsen these effects. Ask your doctor before taking Adipex-P with diet pills, other stimulants, or medicine to treat attention deficit hyperactivity disorder (ADHD).

Tell your doctor about all medicines you use, and those you start or stop using during your treatment with Adipex-P, especially:

  • an antidepressant--citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline.

This list is not complete. Other drugs may interact with Adipex-P, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Phentermine Breastfeeding Warnings

Use should be avoided during breastfeeding. Excreted into human milk: Unknown Excreted into animal milk: Data not available Comments: The effects in the nursing infant are unknown.

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