Adasuve inhalation

Name: Adasuve inhalation

What should I avoid while receiving loxapine inhalation?

Loxapine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Do not drink alcohol. Dangerous side effects could occur.

What other drugs will affect loxapine inhalation?

Using loxapine with other drugs that make you sleepy or slow your breathing can cause dangerous or life-threatening side effects. Ask your doctor before taking a sleeping pill, narcotic pain medicine, prescription cough medicine, a muscle relaxer, or medicine for anxiety, depression, or seizures.

Tell your doctor about all the medicines you have recently used, especially:

  • cold or allergy medicine;

  • medicine to treat Parkinson's disease;

  • medicine to treat excess stomach acid, stomach ulcer, motion sickness, or irritable bowel syndrome;

  • bladder or urinary medicines; or

  • a bronchodilator or other medicines to treat lung problems such as asthma or COPD.

This list is not complete. Other drugs may interact with loxapine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

What is Adasuve?

Adasuve (loxapine) is an antipsychotic medication. It affects the actions of chemicals in your brain.

Adasuve inhalation powder is used to treat agitation related to schizophrenia or bipolar disorder.

Adasuve inhalation is given only in a hospital or clinic setting where any breathing problems can be quickly treated.

How is Adasuve inhalation given?

A healthcare provider will give you Adasuve in a hospital or clinic setting where you can be quickly treated if any serious side effects occur.

Adasuve inhalation is usually given once every 24 hours as needed.

This medicine comes in a single-use inhaler device. You will be shown how to use this device. Follow all directions carefully.

The inhaler device has a green indicator light on one side and a pull tab at one end. When the pull tab is released the green light will turn on, showing that the device is ready for use.

Once the green light turns on, you must use the inhaler within 15 minutes or the device will deactivate. Do not try to use the inhaler if the green light is off.

While using the Adasuve inhaler device, you may hear a clicking sound and the device may feel warm. These are normal functions. After you have inhaled your dose, the green light will turn off to show that the entire dose has been used.

You will be watched closely for at least 1 hour after using Adasuve, to make sure you do not have any breathing problems.

Each single-use inhaler device of this medicine is for one use only. Throw the device away after one use.

Adasuve dosing information

Usual Adult Dose for Agitated State:

10 mg by oral inhalation once within a 24-hour period

Comments:
-To mitigate the risk of bronchospasm, all patients must be undergo screening and examination prior to administration
-This drug must be administered by a healthcare professional only in an enrolled healthcare facility.

Use: For the acute treatment of agitation associated with schizophrenia or bipolar I disorder.

What happens if I miss a dose?

Since Adasuve inhalation is used when needed, you may need only one dose. This medicine is usually not given more than once in a 24-hour period.

What should I avoid while receiving Adasuve inhalation?

Adasuve may impair your thinking or reactions. Avoid driving or operating machinery until you know how this medicine will affect you.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Dizziness or severe drowsiness can cause falls, fractures, or other injuries.

Do not drink alcohol. Dangerous side effects could occur.

Adasuve inhalation side effects

Get emergency medical help if you have signs of an allergic reaction to Adasuve: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers right away if you have:

  • a light-headed feeling, like you might pass out;

  • blurred vision, tunnel vision, eye pain, or seeing halos around lights;

  • bronchospasm (wheezing, cough, chest tightness, trouble breathing);

  • little or no urination;

  • a seizure (convulsions); or

  • severe nervous system reaction - very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out.

Common Adasuve side effects may include:

  • drowsiness;

  • sore throat; or

  • an unusual or unpleasant taste in the mouth.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Loxapine Identification

Substance Name

Loxapine

CAS Registry Number

1977-10-2

Drug Class

Antipsychotic Agents

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