Adapalene Topical

Name: Adapalene Topical

Differin Side Effects

Common Side Effects of Differin

Most side effects of Differin are likely to occur during the first two to four weeks of treatment.

Tell your doctor if any of the following symptoms become severe or don't go away:

  • Redness
  • Dryness
  • Scaling
  • Burning or stinging
  • Itching

Serious Side Effects of Differin

Call your doctor right away if you experience any of the following serious side effects:

  • Signs of anaphylaxis, a severe allergic reaction (signs may include hives, rash, itching, chest tightness, or swelling of the face, lips, tongue, or throat)

Differin Dosage

Differin comes as a gel or cream to apply to the skin. It's typically used once daily before bedtime.

Follow the instructions on your product label carefully. Don't apply more or less Differin than is recommended.

Be sure to wash your hands before using this medicine. Clean your skin with a mild cleanser and pat it dry. Then, apply a thin layer of Differin to the face.

Try to avoid getting Differin in areas around the eyes, lips, and nose.

Differin Overdose

Symptoms of a Differin overdose may include:

  • Skin redness
  • Scaling
  • Irritation

If you swallow Differin or suspect an overdose, contact a poison control center or emergency room immediately.

You can get in touch with a poison control center at 800-222-1222.

Missed Dose of Differin

If you miss a dose of Differin, apply it as soon as you remember.

But if it's almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule.

Don't apply extra medicine to make up for a missed dose.

Overdose

If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. This medication may be harmful if swallowed.

Commonly used brand name(s)

In the U.S.

  • Differin

Available Dosage Forms:

  • Cream
  • Gel/Jelly
  • Solution
  • Lotion
  • Swab

Therapeutic Class: Antiacne

Chemical Class: Retinoid

Precautions While Using adapalene

During the first 3 weeks you are using adapalene, your acne may seem to get worse before it gets better. Full improvement should be seen within 12 weeks, especially if you use the medicine every day. You should not stop using adapalene if your acne seems worse at first, unless irritation or other symptoms become severe. Check with your doctor if your acne does not improve within 8 to 12 weeks.

Do not apply any topical product to the same area where you are using adapalene, unless otherwise directed by your doctor. If applied to the same area treated with adapalene, the following products may cause mild to severe irritation of the skin:

  • Hair products that irritate the skin, such as permanents or hair removal products
  • Skin products for acne (such as clindamycin or erythromycin) or other skin products containing a peeling agent (such as benzoyl peroxide, resorcinol, salicylic acid, or sulfur)
  • Skin products that cause one to be more sensitive to the sun, such as those containing spices or lime
  • Skin products that are too drying or that contain a large amount of alcohol, such as astringents, cosmetics, shaving creams, or after-shave lotions
  • Skin products that are abrasive, such as some soaps or skin cleansers

Your doctor may ask you to use other topical products, such as benzoyl peroxide, clindamycin, or erythromycin, during your treatment with adapalene. Applying the products at different times of the day will lessen the chance of causing skin irritation.

If your skin becomes too dry or red at any time, discuss with your doctor whether you should continue using adapalene. Applying creams, lotions, or moisturizers as needed helps lessen these skin problems.

During treatment with adapalene, avoid getting too much sun on treated areas and do not use sunlamps. Since your skin may be more prone to sunburn or skin irritation, use sunscreen or sunblocking lotions regularly with a sun protection factor (SPF) of 15 or more. Wear protective clothing against sun, wind, and cold weather.

adapalene Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

More common - especially during the first month of use
  • Burning sensation or stinging of skin
  • dryness and peeling of skin
  • itching of skin
  • redness of skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Rare - more common during the first month of use
  • Worsening of acne

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

What is the most important information I should know about adapalene topical?

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

What should I discuss with my healthcare provider before using adapalene topical?

You should not use this medicine if you are allergic to adapalene.

Ask a doctor or pharmacist if it is safe for you to use this medicine if you have other medical conditions.

It is not known whether adapalene passes into breast milk or if it could harm a nursing baby. Do not use this medicine without a doctor's advice if you are breast-feeding a baby.

It is not known whether adapalene will harm an unborn baby. Do not use this medicine without a doctor's advice if you are pregnant.

Adapalene is not approved for use by anyone younger than 12 years old.

Adapalene topical side effects

Get emergency medical help if you have signs of an allergic reaction: hives, itching; chest pain, difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have:

  • skin redness, stinging, burning, or peeling after sun exposure.

Some side effects may occur during the first 4 weeks of using this medicine. These side effects should become less noticeable with continued use.

Common side effects may include:

  • dry, red, or scaly skin;

  • feeling of warmth and mild stinging or burning;

  • peeling skin; or

  • skin pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

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