Adapalene and benzoyl peroxide topical

Name: Adapalene and benzoyl peroxide topical

What happens if I miss a dose?

Apply the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next dose. Do not use extra medicine to make up the missed dose.

Adapalene and benzoyl peroxide topical side effects

Benzoyl peroxide can cause a rare but serious allergic reaction or severe skin irritation. Stop using this medicine and get emergency medical help if you have: hives, itching; difficult breathing, feeling light-headed; or swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • severe redness or swelling of treated skin;

  • severe burning or stinging; or

  • severe dryness or other skin irritation.

Common side effects (especially during the first 4 weeks of use) may include:

  • dry or scaly skin;

  • skin redness; or

  • mild burning or stinging.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

For the Consumer

Applies to adapalene / benzoyl peroxide topical: topical application gel/jelly

Along with its needed effects, adapalene / benzoyl peroxide topical may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking adapalene / benzoyl peroxide topical:

More common
  • Dryness and peeling of the skin
  • flushing or redness of the skin
  • unusually warm skin
Less common
  • Blistering, burning, crusting, or flaking of the skin
  • burning, itching, redness, skin rash, swelling, or soreness at the application site
  • scaling, severe redness, or swelling of the skin
Incidence not known
  • Skin pain
  • sunburn

Some side effects of adapalene / benzoyl peroxide topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known
  • Burning, dry, or itching eyes
  • change in the color of the treated skin
  • discharge or excessive tearing
  • redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid
  • skin rash, encrusted, scaly, and oozing
  • swelling of the face

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dialysis

Data not available

Adapalene / benzoyl peroxide topical Breastfeeding Warnings

Caution is recommended. Excreted into human milk: Unknown Excreted into animal milk: Yes (adapalene); Unknown (benzoyl peroxide) Comment: -This drug should be used in areas away from the chest to prevent accidental contact with the infant's skin.

Risk to the nursing infant is considered low, as only a negligible amount is absorbed after topical application.

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