Acyclovir and hydrocortisone Topical application

Name: Acyclovir and hydrocortisone Topical application

Proper Use of acyclovir and hydrocortisone

Use acyclovir and hydrocortisone only as directed by your doctor to benefit your condition as much as possible. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered.

acyclovir and hydrocortisone comes with a patient information insert. Read and follow the instructions carefully. Ask your doctor if you have any questions.

acyclovir and hydrocortisone is only for cold sores on the lips and around the mouth. Do not get it in your eyes, inside your mouth or nose, or on the genital area. If the cream does get on these areas, rinse it off with water right away.

To help clear up your herpes infection, keep using acyclovir and hydrocortisone for the full time of treatment, even if your symptoms begin to clear up after a few days. Do not miss any doses.

To use:

  • Wash your hands with soap and water before and after using the cream.
  • Clean and dry the affected area before applying the cream.
  • Apply a thin layer to the affected area that covers the cold sore.
  • Do not rub the cream into the cold sore. Rubbing may spread the virus to other areas around your mouth or make your cold sore worse.
  • Do not cover the cold sore or the area around the cold sore with a bandage.
  • Do not bathe, shower, or swim until 30 minutes after applying the medicine.

Dosing

The dose of acyclovir and hydrocortisone will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of acyclovir and hydrocortisone. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For topical dosage form (cream):
    • For cold sores:
      • Adults and children 6 years of age and older—Apply to the affected area 5 times per day for 5 days.
      • Children younger than 6 years of age—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of acyclovir and hydrocortisone, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

acyclovir and hydrocortisone Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Rare
  • Burning, itching, redness, rash, swelling, soreness, or tingling at the application site
  • change in skin color at the application site
  • dryness or flaking of the skin
  • flushing or redness of the skin
  • unusually warm skin
Incidence not known
  • Blistering, burning, or crusting of the skin
  • itching, scaling, severe redness, soreness, or swelling of the skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

For the Consumer

Applies to acyclovir / hydrocortisone topical: topical application cream

Along with its needed effects, acyclovir / hydrocortisone topical may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking acyclovir / hydrocortisone topical:

Rare
  • Burning, itching, redness, rash, swelling, soreness, or tingling at the application site
  • change in skin color at the application site
  • dryness or flaking of the skin
  • flushing or redness of the skin
  • unusually warm skin
Incidence not known
  • Blistering, burning, or crusting of the skin
  • itching, scaling, severe redness, soreness, or swelling of the skin

Renal Dose Adjustments

Data not available

Other Comments

Administration advice:
-Avoid unnecessary rubbing of affected area to avoid aggravating or transferring infection.
-For cutaneous use only for herpes labialis of the lips and around the mouth; not to be used in the eye, inside the mouth or nose, or on the genitals.

Storage requirements:
-Store at controlled room temperature; do not freeze.

Patient advice:
-Seek medical advice if a cold sore fails to heal within 2 weeks.

Acyclovir / hydrocortisone topical Pregnancy Warnings

The manufacturer makes no recommendation regarding use during pregnancy. US FDA pregnancy category: B

Animal studies have failed to reveal evidence of teratogenicity following use of acyclovir. Corticosteroids have been found to be teratogenic in animals when administered systemically at relatively low doses. Systemic exposure of acyclovir and hydrocortisone following topical administration is minimal. There are no controlled data in human pregnancy. US FDA pregnancy category B: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.

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