Acticin

Name: Acticin

What should I avoid while using Acticin (permethrin topical)?

Rinse with water if this medicine gets in your eyes.

Lice and scabies infections are highly contagious. Avoid sexual or intimate contact with others until your lice or scabies infection has cleared up. Avoid sharing hair brushes, combs, hair accessories, hats, clothing, bed linens, and other articles of personal use.

Avoid using other medications on the areas you treat with permethrin topical, unless your doctor tells you to.

What other drugs will affect Acticin (permethrin topical)?

It is not likely that other drugs you take orally or inject will have an effect on topically applied permethrin topical. But many drugs can interact with each other. Tell each of your health care providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

Consumer Information Use and Disclaimer

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about this medicine, please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

This information should not be used to decide whether or not to take Acticin or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Acticin. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

Review Date: October 4, 2017

Indications

Acticin (permethrin) Cream 5% is indicated for the treatment of infestation with Sarcoptes scabiei (scabies).

Pregnancy & Lactation

Pregnancy Category: B

Lactation: Not known if distributed in breast milk; may temporarily withhold the drug while the mother is nursing

Pregnancy Categories

A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA:Information not available.

Side effects

In clinical trials, generally mild and transient burning and stinging followed application with permethrin cream in 10% of patients and was associated with the severity of infestation. Pruritis was reported in 7% of patients at various times post- application. Erythema, numbness, tingling, and rash were reported in 1 to 2% or less of patients (see PRECAUTIONS: General).

Read the entire FDA prescribing information for Acticin (Permethrin)

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For Healthcare Professionals

Applies to permethrin topical: topical cream, topical kit, topical lotion, topical solution, topical spray

Local

Local side effects have included mild and transient burning and stinging usually associated with the severity of infestation.[Ref]

Dermatologic

Dermatological side effects have included pruritus (7%), erythema (1% to 2%), and rash (1% to 2%).[Ref]

Nervous system

Nervous system side effects have included numbness and tingling (1% to 2%). Headache and dizziness have also been reported. Rare occurrences of seizure have been reported; however, an association with the use of permethrin topical (the active ingredient contained in Acticin) has not been confirmed.[Ref]

Gastrointestinal

Gastrointestinal side effects have included abdominal pain, diarrhea, and nausea and/or vomiting.[Ref]

General

General side effects have included fever.[Ref]

Some side effects of Acticin may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Usual Adult Dose for Scabies

Permethrin topical 5% cream:
Thoroughly massage into the skin from the neck to the soles of the feet. The cream should be removed by washing (shower or bath) after 8 to 14 hours.

Usual Pediatric Dose for Scabies

Permethrin topical 5% cream
Infants: Thoroughly massage along the hairline, neck, temple, and forehead. The cream should be removed by washing after 8 to 14 hours.

Usual Pediatric Dose for Lice

Permethrin topical 1% kit:
2 months or older: Apply lotion/creme rinse to shampooed and towel-dried hair until hair and scalp are saturated (especially behind the ears and on the nape of the neck). Leave on hair for 10 minutes and rinse with water. Use comb and/or gloves provided to remove remaining nits.

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