Acetaminophen, dextromethorphan, and doxylamine

Name: Acetaminophen, dextromethorphan, and doxylamine

What is acetaminophen, dextromethorphan, and doxylamine?

Acetaminophen is a pain reliever and fever reducer.

Dextromethorphan is a cough suppressant. It affects the cough reflex in the brain that triggers coughing.

Doxylamine is an antihistamine that reduces the effects of the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Acetaminophen, dextromethorphan, and doxylamine is a combination medicine used to treat headache, fever, body aches, cough, runny nose, sneezing, and sore throat caused by allergies, the common cold, or the flu.

This medicine will not treat a cough that is caused by smoking, asthma, or emphysema.

Acetaminophen, dextromethorphan, and doxylamine may also be used for purposes not listed in this medication guide.

How should I take acetaminophen, dextromethorphan, and doxylamine?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use for longer than recommended. Cough and cold medicine is usually taken only for a short time until your symptoms clear up.

Do not take more of this medication than is recommended. An overdose of acetaminophen can damage your liver or cause death.

Measure liquid medicine with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

Stop taking the medicine and call your doctor if you still have a sore throat after 2 days, or if you have a fever, headache, rash, nausea, or vomiting.

If you need surgery or medical tests, tell the surgeon or doctor ahead of time if you have taken this medicine within the past few days.

Store at room temperature away from moisture and heat. Do not allow liquid medicine to freeze.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of acetaminophen can be fatal.

The first signs of an acetaminophen overdose include loss of appetite, nausea, vomiting, stomach pain, sweating, and confusion or weakness. Later symptoms may include pain in your upper stomach, dark urine, and yellowing of your skin or the whites of your eyes.

Usual Adult Dose for Pain

Acetaminophen/dextromethorphan/doxylamine 1000 mg-30 mg-12.5 mg/30 mL oral liquid:
30 mL orally every 6 hours not to exceed 120 mL daily.

Acetaminophen/dextromethorphan/doxylamine 325 mg-15 mg- 6.25 mg oral capsule:
2 capsules every 6 hours as needed not to exceed 8 capsules/day.

Acetaminophen/dextromethorphan/doxylamine 325 mg-15 mg-6.25 mg/15 mL oral liquid:
30 mL orally every 6 hours not to exceed 120 mL daily.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

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