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What should I discuss with my healthcare provider before using benzoyl peroxide and clindamycin topical?
You should not use this medicine if you are allergic to benzoyl peroxide or clindamycin (Cleocin, Clina-Derm, Clindets).
Although this medicine is applied to the skin, your body may absorb enough clindamycin to cause serious side effects. You may not be able to use this medicine if you have:
inflammation of your intestines (also called enteritis);
ulcerative colitis; or
if you have ever had severe diarrhea caused by antibiotic medicine.
It is not known whether benzoyl peroxide and clindamycin topical will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.
It is not known whether benzoyl peroxide and clindamycin topical passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.
What do I need to tell my doctor BEFORE I take Acanya?
- If you have an allergy to clindamycin, benzoyl peroxide, or any other part of Acanya (clindamycin and benzoyl peroxide gel (10-week storage)).
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you have ever had any of these health problems: Very loose stools called antibiotic-associated colitis, regional enteritis, ulcerative colitis, or Crohn's disease.
- If you are using any products that have erythromycin.
This is not a list of all drugs or health problems that interact with this medicine.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Acanya with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
How is this medicine (Acanya) best taken?
Use Acanya as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Do not take this medicine by mouth. Use on your skin only. Keep out of your mouth, nose, and eyes (may burn).
- If you get Acanya in any of these areas, rinse well with water.
- Wash your hands before and after use.
- Clean affected part before use. Make sure to dry well.
- Put a thin layer on the affected skin and rub in gently.
- Do not put on cuts, scrapes, or damaged skin.
- To gain the most benefit, do not miss doses.
What do I do if I miss a dose?
- Put on a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not put on 2 doses or extra doses.
How do I store and/or throw out Acanya?
- Store at room temperature. Do not freeze.
- Store in a dry place. Do not store in a bathroom.
- Store upright with the cap on.
- Throw away any part not used after 10 weeks.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Check with your pharmacist about how to throw out unused drugs.
Acanya Dosage and Administration
Apply a pea-sized amount of Acanya Gel to the face once daily.
Use of Acanya Gel beyond 12 weeks has not been evaluated.
Concomitant topical acne therapy should be used with caution because a possible cumulative irritancy effect may occur, especially with the use of peeling, desquamating, or abrasive agents.
Acanya Gel is not for oral, ophthalmic, or intravaginal use.
Acanya Gel is contraindicated in those individuals who have shown hypersensitivity to clindamycin, benzoyl peroxide, any components of the formulation, or lincomycin. Anaphylaxis, as well as allergic reactions leading to hospitalization, has been reported in postmarketing use with Acanya Gel [see Adverse Reaction (6.2)].
Acanya Gel is contraindicated in patients with a history of regional enteritis, ulcerative colitis, or antibiotic-associated colitis [see Warnings and Precautions (5.1)].
Acanya (clindamycin phosphate and benzoyl peroxide) Gel, 1.2%/2.5% is a combination product with two active ingredients in a white to off-white, opague, smooth aqueous gel formulation intended for topical use. Clindamycin phosphate is a water-soluble ester of the semi-synthetic antibiotic produced by a 7(S)-chloro-substitution of the 7(R)-hydroxyl group of the parent antibiotic lincomycin.
The chemical name for clindamycin phosphate is Methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-α-D-galacto-octopyranoside 2-(dihydrogen phosphate). The structural formula for clindamycin phosphate is represented below:
Molecular Formula: C18H34ClN2O8PS Molecular Weight: 504.97
Benzoyl peroxide is an antibacterial and keratolytic agent. The structural formula for benzoyl peroxide is represented below:
Molecular Formula: C14H10O4 Molecular Weight: 242.23
Acanya Gel contains the following inactive ingredients: purified water, carbomer 980, propylene glycol, and potassium hydroxide. Each gram of Acanya Gel contains 1.2% of clindamycin phosphate which is equivalent to 1% clindamycin.
What is Acanya?
Acanya Gel contains a combination of benzoyl peroxide and clindamycin. Benzoyl peroxide has an antibacterial effect. It also has a mild drying effect that allows excess oil and dirt to be washed away. Clindamycin is an antibiotic that prevents bacteria from growing on the skin.
Acanya Gel is used to treat acne vulgaris in patients 12 years or older.
Acanya may also be used for purposes not listed in this medication guide.