Abacavir, lamivudine, and zidovudine
Name: Abacavir, lamivudine, and zidovudine
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- Abacavir, lamivudine, and zidovudine side effects
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- Abacavir, lamivudine, and zidovudine adverse effects
- Abacavir, lamivudine, and zidovudine 300 mg
- Abacavir, lamivudine, and zidovudine and side effects
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
Do not allow your medicine to run out completely before you get your prescription refilled. It is important that you not stop taking the medicine once you have started. If you miss several doses, you may have a dangerous or even fatal allergic reaction once you start taking this medicine again.
abacavir, lamivudine, and zidovudine Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:More common
- Abdominal or stomach pain
- muscle weakness
- numbness or tingling of the face, feet, or hands
- pain in the joints
- pain in the muscles
- pale skin
- skin rash
- sore throat
- swelling of the feet or lower legs
- unusual feeling of discomfort or illness
- unusual tiredness or weakness
- yellow eyes or skin
- Black, tarry stools
- blood in the urine or stools
- pinpoint red spots on the skin
- unusual bleeding or bruising
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:More common
- Bone pain
- loss of appetite
- trouble sleeping
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
What are some things I need to know or do while I take Abacavir, Lamivudine, and Zidovudine?
- Tell all of your health care providers that you take abacavir, lamivudine, and zidovudine. This includes your doctors, nurses, pharmacists, and dentists.
- This medicine may raise the chance of heart attack. Talk with the doctor.
- Use care if you have risks for heart disease (high blood pressure, high cholesterol, overweight, high blood sugar or diabetes, cigarette smoking, man older than 40 years of age, other family members with early heart disease, woman after change of life). Talk with your doctor.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- If this medicine is stopped because you have an allergy to it, do not restart it. It may not be safe to restart abacavir, lamivudine, and zidovudine. Throw away any of this medicine that you have not taken. If you are not sure how to throw away unused drugs, check with your pharmacist.
- If abacavir, lamivudine, and zidovudine is stopped for any other reason, do not restart it without talking to the doctor. It could be very risky to restart on your own.
- Do not run out of this medicine.
- Talk with your doctor before you drink alcohol.
- This medicine is not a cure for HIV. Stay under the care of your doctor.
- This medicine does not stop the spread of diseases like HIV or hepatitis that are passed through blood or having sex. Do not have any kind of sex without using a latex or polyurethane condom. Do not share needles or other things like toothbrushes or razors. Talk with your doctor.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using abacavir, lamivudine, and zidovudine while you are pregnant.
How is this medicine (Abacavir, Lamivudine, and Zidovudine) best taken?
Use this medicine as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Take with or without food.
- Keep taking abacavir, lamivudine, and zidovudine as you have been told by your doctor or other health care provider, even if you feel well.
- It is important that you do not miss or skip a dose of this medicine during treatment.
- If you have trouble swallowing, talk with your doctor.
What do I do if I miss a dose?
- Take a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
- If you are not sure what to do if you miss a dose, call your doctor.
Consumer Information Use and Disclaimer
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time abacavir, lamivudine, and zidovudine is refilled. If you have any questions about this medicine, please talk with the doctor, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
This information should not be used to decide whether or not to take abacavir, lamivudine, and zidovudine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to abacavir, lamivudine, and zidovudine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.
Review Date: October 4, 2017
Excipient information presented when available (limited, particularly for generics); consult specific product labeling.
Trizivir: Abacavir sulfate 300 mg, lamivudine 150 mg, and zidovudine 300 mg [contains fd&c blue #2 (indigotine)]
Generic: Abacavir sulfate 300 mg, lamivudine 150 mg, and zidovudine 300 mg
Refer to adult dosing.
Administer without regard to food.
In general, women who become pregnant on a stable combination antiretroviral therapy (cART) regimen may continue that regimen if viral suppression is effective, appropriate drug exposure can be achieved, contraindications for use in pregnancy are not present, and the regimen is well tolerated. The Health and Human Services (HHS) Perinatal HIV Guidelines generally do not recommend this combination as initial therapy in antiretroviral-naive pregnant women due to inferior virologic activity (HHS [perinatal] 2016). See individual agents.
• Discuss specific use of drug and side effects with patient as it relates to treatment. (HCAHPS: During this hospital stay, were you given any medicine that you had not taken before? Before giving you any new medicine, how often did hospital staff tell you what the medicine was for? How often did hospital staff describe possible side effects in a way you could understand?)
• Patient may experience headache, joint pain, anxiety, drowsiness, nausea, vomiting, or diarrhea. Have patient report immediately to prescriber signs of allergic reaction with organ failure (fever, rash, fatigue, flu-like signs, nausea, vomiting, diarrhea, abdominal pain, pharyngitis, cough, or difficulty breathing), signs of bone marrow depression (neutropenia or anemia), signs of liver problems (dark urine, fatigue, lack of appetite, nausea, abdominal pain, light-colored stools, vomiting, or jaundice), signs of lactic acidosis (fast breathing, tachycardia, abnormal heartbeat, vomiting, fatigue, shortness of breath, severe loss of strength and energy, severe dizziness, feeling cold, or muscle pain or cramps), signs of pancreatitis (severe abdominal pain, severe back pain, severe nausea, or vomiting), signs of kidney problems (urinary retention, hematuria, change in amount of urine passed, or weight gain), loss of strength or energy, angina, depression, severe dizziness, passing out, mouth sores, muscle pain, burning or numbness feeling, shortness of breath, edema, change in body fat, or signs of infection (HCAHPS).
• Educate patient about signs of a significant reaction (eg, wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat). Note: This is not a comprehensive list of all side effects. Patient should consult prescriber for additional questions.
Intended Use and Disclaimer: Should not be printed and given to patients. This information is intended to serve as a concise initial reference for healthcare professionals to use when discussing medications with a patient. You must ultimately rely on your own discretion, experience and judgment in diagnosing, treating and advising patients.