Name: A-Spaz

How is this medicine (A-Spaz) best taken?

Use this medicine as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • Take 30 to 60 minutes before meals.
  • Do not take antacids at the same time as A-Spaz. Ask your doctor if you have a question about how to take antacids with this medicine.
  • Place tablet under the tongue and let melt.
  • Some tablets may also be chewed or swallowed whole. Check with your pharmacist if you have questions about how to take A-Spaz.

What do I do if I miss a dose?

  • If you take this medicine on a regular basis, take a missed dose as soon as you think about it.
  • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
  • Do not take 2 doses at the same time or extra doses.
  • Many times A-Spaz (hyoscyamine sublingual tablets) is used on an as needed basis. Do not use more often than told by the doctor.

Consumer Information Use and Disclaimer

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about this medicine, please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

This information should not be used to decide whether or not to take A-Spaz or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to A-Spaz. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

Review Date: October 4, 2017

For the Consumer

Applies to hyoscyamine: oral conventional tablets and sublingual tablets, oral extended-release capsules and tablets, oral oral solution and elixir, oral orally disintegrating tablets, parenteral injection

Side effects include:

Most adverse effects are manifestations of pharmacologic effects at muscarinic-cholinergic receptors and usually are reversible when therapy is discontinued.

Severity and frequency of adverse effects are dose related and individual intolerance varies greatly; adverse effects occasionally may be obviated by a reduction in dosage but this also may eliminate potential therapeutic effects.

Adverse effects include dry mouth, urinary hesitancy and retention, blurred vision, tachycardia, palpitations, mydriasis, increased ocular tension, loss of taste, headache, nervousness, drowsiness, weakness, fatigue, dizziness, insomnia, nausea, vomiting, impotence, constipation, bloated feeling, abdominal pain, diarrhea, allergic reactions or drug idiosyncrasies, urticaria and other dermal manifestations, ataxia, speech disturbance, mental confusion and/or excitement (especially in geriatric patients), short-term memory loss, hallucinations, and decreased sweating.

Usual Adult Dose for Anesthesia

5 mcg/kg administered 30 to 60 minutes prior to the time of induction of anesthesia or given at the time the preanesthetic narcotic or sedative are administered.

Usual Pediatric Dose for Anesthesia

5 mcg/kg administered 30 to 60 minutes prior to the time of induction of anesthesia or given at the time the preanesthetic narcotic or sedative are administered.

Renal Dose Adjustments

Data not available

Hyoscyamine Pregnancy Warnings

Hyoscyamine has been assigned to pregnancy category C by the FDA. Animal studies have not been reported. There are no controlled data in human pregnancy. Hyoscyamine is only recommended for use during pregnancy when there are no alternatives and benefit outweighs risk.

Hyoscyamine Breastfeeding Warnings

There are no data on the excretion of hyoscyamine into human milk. Some experts recommend cautious use of hyoscyamine during breast-feeding due to the sensitivity of the neonate to anticholinergic agents (probably because of immaturity of motor endplates). Hyoscyamine is considered compatible with breast-feeding by the American Academy of Pediatrics.